Organophosphate-induced brain injuries: delayed apoptosis mediated by nitric oxide.

Abstract

The features of organophosphate-induced brain injuries were investigated. Rats were poisoned intraperitoneally with 9 mg/kg (1.8 LD(50)) of diisopropylfluorophosphate. Pyridostigmine bromide (0.1 mg/kg) and atropine methylnitrate (20 mg/kg), which are centrally inactive, were pre-treated intramuscularly to reduce the mortality and eliminate peripheral signs… (More)

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Cite this paper

@article{Kim1999OrganophosphateinducedBI, title={Organophosphate-induced brain injuries: delayed apoptosis mediated by nitric oxide.}, author={Y-S Kim and G. H. Hur and Seung W. Shin and D E Sok and J-H Kang and Young-Sun Lee}, journal={Environmental toxicology and pharmacology}, year={1999}, volume={7 2}, pages={147-52} }