Organophosphate esters in East Greenland polar bears and ringed seals: Adipose tissue concentrations and in vitro depletion and metabolite formation.

@article{Strobel2018OrganophosphateEI,
  title={Organophosphate esters in East Greenland polar bears and ringed seals: Adipose tissue concentrations and in vitro depletion and metabolite formation.},
  author={Adelle Strobel and William G Willmore and Christian Sonne and Rune Dietz and Robert J Letcher},
  journal={Chemosphere},
  year={2018},
  volume={196},
  pages={240-250}
}
East Greenland is a contamination "hot spot" for long-range transported anthropogenic chemicals, including organophosphate esters (OPEs). High concentrations of OPEs have been reported in arctic air while very little is known for wildlife where OPE tissue residues levels appear to be strongly influenced by biotransformation. In the present study, the hepatic in vitro metabolism of six environmentally relevant organophosphate (OP) triesters and corresponding OP diester formation were… CONTINUE READING
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