Organometallic ruthenium(II) arene compounds with antiangiogenic activity.

Abstract

The antimetastatic ruthenium(II) compounds [Ru(η(6)-p-cymene)Cl(2)(PTA)] (PTA = 1,3,5-triaza-7-phosphaadamantane) (RAPTA-C) and [Ru(η(6)-toluene)Cl(2)(PTA)] (RAPTA-T), as well as their analogues [Ru(η(6)-p-cymene)Cl(2)(DAPTA)] (DAPTA = (3,7-diacetyl-1,3,7-triaza-5-phosphabicyclo[3.3.1]nonane)) (DAPTA-C) and [Ru(η(6)-toluene)Cl(2)(DAPTA)] (DAPTA-T… (More)
DOI: 10.1021/jm2002074

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Cite this paper

@article{NowakSliwinska2011OrganometallicRA, title={Organometallic ruthenium(II) arene compounds with antiangiogenic activity.}, author={Patrycja Nowak-Sliwinska and Judy R. van Beijnum and Angela Casini and Alexey A Nazarov and Georges Wagni{\`e}res and Hubert E van den Bergh and Paul J Dyson and Arjan W. Griffioen}, journal={Journal of medicinal chemistry}, year={2011}, volume={54 11}, pages={3895-902} }