Organoids as a model system for studying human lung development and disease.

  title={Organoids as a model system for studying human lung development and disease.},
  author={Rohan R. Nadkarni and Soumeya Abed and Jonathan Draper},
  journal={Biochemical and biophysical research communications},
  volume={473 3},
The lung is a complex organ comprising multiple cell types that perform a variety of vital processes, including immune defense and gas exchange. Diseases of the lung, such as chronic obstructive pulmonary disease, asthma and lung cancer, together represent one of the largest causes of patient suffering and mortality. Logistical barriers that hamper access to embryonic, normal adult or diseased lung tissue currently hinder the study of lung disease. In vitro lung modeling represents an… CONTINUE READING
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