Organoids: Modelling polycystic kidney disease.

  title={Organoids: Modelling polycystic kidney disease.},
  author={Paola Romagnani},
  journal={Nature materials},
  volume={16 11},
The kidney is a highly complex organ with a range of fundamental roles in filtration and homeostasis of the human body. There are a multitude of diseases that affect the normal functioning of kidneys. In particular, over 150 distinct genetic diseases can cause chronic kidney disease (CKD). However, numerous in vitro and in vivo models do not fully recapitulate the pathophysiology of human CKD due to species-specific variations. In this context, Benjamin Freedman and colleagues1 now report in… CONTINUE READING
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