Organochlorine chemicals and neurodegeneration among elderly subjects in Costa Rica.

@article{Steenland2014OrganochlorineCA,
  title={Organochlorine chemicals and neurodegeneration among elderly subjects in Costa Rica.},
  author={Kyle N. Steenland and Ana M Mora and Dana Boyd Barr and Jorge L. Juncos and Norbel Rom{\'a}n and Catharina Wesseling},
  journal={Environmental research},
  year={2014},
  volume={134},
  pages={205-9}
}
BACKGROUND We previously screened 400 elderly Costa Ricans for neurodegenerative disease. Those reporting occupational pesticide exposure (18%) had an increased Parkinson׳s disease (PD) risk (OR 2.57, 95% CI 0.91-7.26), and worse cognition (Mini-Mental States Exam (MMSE) 24.5 versus 25.9 points, p=0.01). We subsequently measured long-lasting organochlorine pesticides (β-HCH, DDE, DDT, and dieldrin) in a sub-sample (n=89). Dieldrin and β-HCH have been linked to PD, and DDE to Alzheimer׳s disease… CONTINUE READING
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