Organocatalytic enantioselective β-functionalization of aldehydes by oxidation of enamines and their application in cascade reactions.

Abstract

Iminium catalysis, involving the transformation of iminium ions to enamines, has been extensively studied in the context of a number of organic processes. However, the reverse of this process involving conversion of enamines to iminium species has not been realized. Here, we describe a new transformation-'oxidative enamine catalysis'-in which direct… (More)
DOI: 10.1038/ncomms1214

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@article{Zhang2011OrganocatalyticE, title={Organocatalytic enantioselective β-functionalization of aldehydes by oxidation of enamines and their application in cascade reactions.}, author={Shi-lei Zhang and He-Xin Xie and Jin Zhu and Hao Nan Li and Xin-Shuai Zhang and Jian Li and Wei Wang}, journal={Nature communications}, year={2011}, volume={2}, pages={211} }