Organocatalytic asymmetric Michael addition of 2,4-pentandione to nitroolefins.

Abstract

[reaction: see text] A novel binaphthyl-derived amine thiourea organocatalyst has been developed and demonstrated to efficiently catalyze Michael addition reactions (using as low as 1 mol % loading) of diketones to nitroalkenes with remarkably high enantioselectivities. 

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Cite this paper

@article{Wang2005OrganocatalyticAM, title={Organocatalytic asymmetric Michael addition of 2,4-pentandione to nitroolefins.}, author={Jian Wang and Hao Li and Wenhu Duan and Liansuo Zu and Wei Wang}, journal={Organic letters}, year={2005}, volume={7 21}, pages={4713-6} }