Organizational principles of human visual cortex revealed by receptor mapping.

@article{Eickhoff2008OrganizationalPO,
  title={Organizational principles of human visual cortex revealed by receptor mapping.},
  author={Simon B. Eickhoff and Claudia Rottschy and Milenko Kujovic and Nicola Palomero-Gallagher and Karl Zilles},
  journal={Cerebral cortex},
  year={2008},
  volume={18 11},
  pages={
          2637-45
        }
}
This receptorarchitectonic study of the human visual cortex investigated interareal differences in mean receptor concentrations and laminar distribution patterns of 16 neurotransmitter receptors in the dorsal and ventral parts of areas V1, V2, V3 as well as in adjoining areas V4 (ventrally) and V3A (dorsally). Both the functional hierarchy of these areas and a distinction between dorsal and ventral visual cortices were reflected by significant receptorarchitectonic differences. The observation… 

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References

SHOWING 1-10 OF 63 REFERENCES
Ventral visual cortex in humans: Cytoarchitectonic mapping of two extrastriate areas
TLDR
These maps can now be used to identify the anatomical correlates of functional activations observed in neuroimaging experiments to enable a more informed investigation into the many open questions regarding the organization of the human visual cortex.
Connectional and Architectonic Evidence for Dorsal and Ventral V3, and Dorsomedial Area in Marmoset Monkeys
The existence of a third visual area, V3, along the outer margin of V2 was originally proposed for primates on the basis of projections from V1. The evidence for V3 was never totally convincing
Morphological variation of layer III pyramidal neurones in the occipitotemporal pathway of the macaque monkey visual cortex.
TLDR
The findings suggest the possibility that the complex response properties of neurones in rostral stations in the occipitotemporal pathway may be attributed to their larger and more complex basal dendritic fields, and to the increase in both number and density of spines on their basal dends.
Functional measurements of human ventral occipital cortex: retinotopy and colour.
TLDR
Functional magnetic resonance imaging was used to identify visual field maps and colour responsivity on the ventral surface and found a visual map of the complete contralateral hemifield in a 4 cm(2) region adjacent to ventral V3; the foveal representation of this map is confluent with that of areas V1/2/3.
Retinotopy and color sensitivity in human visual cortical area V8
TLDR
The location of the human color-selective region did not match the location of area V4 (neither its dorsal nor ventral subdivisions), as extrapolated from macaque maps, and instead this region coincides with a new retinotopic area that is called 'V8', which includes a distinct representation of the fovea and both upper and lower visual fields.
Third tier ventral extrastriate cortex in the New World monkey, Cebus apella
TLDR
Observations argue against the idea that V3v is an area restricted to the ventral cortex in New World monkeys and support the conclusions of previous anatomical studies in Cebus that showed a continuity of myeloarchitecture and connectional patterns between ventral and lateral extrastriate cortices.
Topographic Organization in and near Human Visual Area V4
TLDR
Functional magnetic resonance imaging is used to obtain topographic maps from human subjects, using visual stimuli and tasks designed to maximize accuracy of topographical maps of the fovea and parafoveA and to measure the effects of attention on topographicMaps are identified.
Processing of color, form and disparity information in visual areas VP and V2 of ventral extrastriate cortex in the macaque monkey
TLDR
The responses of single cells to light bars of different orientation, direction of motion, speed, binocular disparity, and wavelength were systematically analyzed in areas V2 and VP of ventral extrastriate visual cortex in the macaque monkey, suggesting a significant asymmetry in the way visual information is processed in upper and lower parts of the visual field.
...
...