Organization of the gene encoding the human Kell blood group protein.

@article{Lee1995OrganizationOT,
  title={Organization of the gene encoding the human Kell blood group protein.},
  author={S Lee and E D Zambas and Eric D. Green and Colvin M. Redman},
  journal={Blood},
  year={1995},
  volume={87 11},
  pages={4922}
}
Kell is one of the major blood group systems in human erythrocytes. It is a complex system containing a large number of different antigens. Previously we cloned the Kell cDNA, which was predicted to encode an integral membrane protein with 731 amino acids. Now we have isolated overlapping genomic clones and determined the exon-intron structure of the KEL gene; it spans approximately 21.5 kb with its coding sequence being organized in 19 exons that range in size from 63 bp to 288 bp. The size of… CONTINUE READING