Organization of the G protein-coupled receptors rhodopsin and opsin in native membranes.

  title={Organization of the G protein-coupled receptors rhodopsin and opsin in native membranes.},
  author={Yan Liang and Dimitrios I. Fotiadis and Sławomir Filipek and David A. Saperstein and Krzysztof Palczewski and Andreas H. Engel},
  journal={The Journal of biological chemistry},
  volume={278 24},
G protein-coupled receptors (GPCRs), which constitute the largest and structurally best conserved family of signaling molecules, are involved in virtually all physiological processes. Crystal structures are available only for the detergent-solubilized light receptor rhodopsin. In addition, this receptor is the only GPCR for which the presumed higher order oligomeric state in native membranes has been demonstrated (Fotiadis, D., Liang, Y., Filipek, S., Saperstein, D. A., Engel, A., and… CONTINUE READING
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  • R. G. Matthews, R. Hubbard, K. P. Brown, G. Wold
  • J. Gen. Physiol
  • 1963
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