Organization of single components of defensive behaviors within distinct columns of periaqueductal gray matter of the rat: role of N-methyl-D-aspartic acid glutamate receptors.

@article{Bittencourt2004OrganizationOS,
  title={Organization of single components of defensive behaviors within distinct columns of periaqueductal gray matter of the rat: role of N-methyl-D-aspartic acid glutamate receptors.},
  author={Athelson Stefanon Bittencourt and Antonio de P{\'a}dua Carobrez and L P Zamprogno and Sergio Brasil Tufik and Luiz Carlos Schenberg},
  journal={Neuroscience},
  year={2004},
  volume={125 1},
  pages={71-89}
}
The periaqueductal gray matter (PAG) is functionally organized in longitudinal columns arranged along the aqueduct. Stimulation of lateral and dorsal columns produces a complex set of unconditioned behaviors named the 'defense reaction.' Overt responses in rats comprise a tense immobile display, fully opened eyes (herein named exophthalmus), trotting, galloping, jumping, micturition and defecation. Besides, the PAG is rich in glutamate and respective receptors, including the N-methyl-d-aspartic… CONTINUE READING