Organization of extracellular matrix in epiphyseal growth plate.

@article{Eisenstein1971OrganizationOE,
  title={Organization of extracellular matrix in epiphyseal growth plate.},
  author={Reuben Eisenstein and Nino Sorgente and Klaus E. Kuettner},
  journal={The American journal of pathology},
  year={1971},
  volume={65 3},
  pages={
          515-34
        }
}
Three cations of varying size and charge density, egg-white lysozyme, protamine and ruthenium red, were used to stain the extracellular matrix of epiphyseal cartilage growth plate. With these stains, it was possible to distinguish three types of proteoglycans or materials associated with them, which may well have as their major differences the type of cross linking to the tissue. One type was stained by ruthenium red and protamine but not by lysozyme, was extractable with 3 M guanidinium… CONTINUE READING

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