Organization of cytoskeleton elements during herpes simplex virus type 1 infection of human fibroblasts: an immunofluorescence study.

@article{Norrild1986OrganizationOC,
  title={Organization of cytoskeleton elements during herpes simplex virus type 1 infection of human fibroblasts: an immunofluorescence study.},
  author={Bodil Norrild and V. P. Lehto and Ismo Virtanen},
  journal={The Journal of general virology},
  year={1986},
  volume={67 ( Pt 1)},
  pages={97-105}
}
Cultured human fibroblasts showed a typical fibrillar organization of microtubules in immunofluorescence, including the vimentin type of intermediate filament as well as actin-containing microfilaments. During infection with herpes simplex virus type 1 (HSV-1), the vimentin organization was maintained whereas actin, myosin and tubulin showed a progressive association with the viral glycoproteins within juxtanuclear structures. These structures could also be revealed with fluorochrome-coupled… CONTINUE READING

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