Organization and remodeling of the olivocerebellar climbing fiber projection

@article{Sugihara2006OrganizationAR,
  title={Organization and remodeling of the olivocerebellar climbing fiber projection},
  author={Izumi Sugihara},
  journal={The Cerebellum},
  year={2006},
  volume={5},
  pages={15-22}
}
Climbing fibers, terminal portions of the axons of inferior olive neurons, form strong synaptic connections to Purkinje cells in an exclusive one-to-one relationship. This projection is established during development by drastic reshaping in each climbing fiber and in overall axonal arborization. Early climbing fibers form loose ‘creeper’-type terminal arbors that seem to make weak contact with many Purkinje cells in the first postnatal week. The terminal arbor then becomes focused on a single… CONTINUE READING
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