Organization and Regulation of Mitochondrial Protein Synthesis.

  title={Organization and Regulation of Mitochondrial Protein Synthesis.},
  author={Martin A. Ott and Alexey Amunts and Alan Brown},
  journal={Annual review of biochemistry},
Mitochondria are essential organelles of endosymbiotic origin that are responsible for oxidative phosphorylation within eukaryotic cells. Independent evolution between species has generated mitochondrial genomes that are extremely diverse, with the composition of the vestigial genome determining their translational requirements. Typically, translation within mitochondria is restricted to a few key subunits of the oxidative phosphorylation complexes that are synthesized by dedicated ribosomes… CONTINUE READING
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