Organization, inducible-expression and chromosome localization of the human HMG-I(Y) nonhistone protein gene.

@article{Friedmann1993OrganizationIA,
  title={Organization, inducible-expression and chromosome localization of the human HMG-I(Y) nonhistone protein gene.},
  author={Michael Friedmann and Laurel T. Holth and Huda Y. Zoghbi and Raymond Reeves},
  journal={Nucleic acids research},
  year={1993},
  volume={21 18},
  pages={4259-67}
}
Members of the HMG-I(Y) family of mammalian nonhistone proteins are of importance because they have been demonstrated to bind specifically to the minor groove of A.T-rich sequences both in vitro and in vivo and to function as gene transcriptional regulatory proteins in vivo. Here we report the cloning, sequencing, characterization and chromosomal localization of the human HMG-I(Y) gene. The gene has several potential promoter/enhancer regions, a number of different transcription start sites and… CONTINUE READING