Organism specific Amino Acid Substitution Matrices

  title={Organism specific Amino Acid Substitution Matrices},
  author={john. edwards}
Amino acid substitution matrices are widely used in the field of computational molecular biology as a means of optimising protein sequence alignments. Examples of substitution matrices include the PAM matrix [DAYHOFF79] and the BLOSUM matrix [HENIKOFF92]. Certain substitution matrices are better suited to certain alignments and one of the most common optimisations is to use a substitution matrix that is tailored to the presumed evolutionary distance between the sequences. The PAM and BLOSUM… CONTINUE READING