Organisation of the mouse sinoatrial node: structure and expression of HCN channels.

@article{Liu2007OrganisationOT,
  title={Organisation of the mouse sinoatrial node: structure and expression of HCN channels.},
  author={Jie Liu and Halina Dobrzynski and Joseph Yanni and Mark R. Boyett and Ming Lei},
  journal={Cardiovascular research},
  year={2007},
  volume={73 4},
  pages={729-38}
}
OBJECTIVE To reveal the structural characteristics of the sinoatrial node (SAN) and the distribution of hyperpolarization-activated cyclic nucleotide-gated cation channels (HCN) in the SAN in the mouse. METHODS The structure of the SAN and the distribution of HCN channels in the SAN in the mouse were studied by histology and immunolabelling of ANP, Cx43 and HCN channels. RESULTS The mouse SAN is a comma-shaped structure with a length of approximately 1.5 mm parallel to the crista terminalis… CONTINUE READING