Organic solvent extracted EmrE solubilized in dodecyl maltoside is monomeric and binds drug ligand.

Abstract

Ethidium multidrug resistance protein (EmrE) is a member of the small multidrug resistance family of proteins and is responsible for resistance to a diverse group of lipophilic cations. To examine the multimeric state(s), size-exclusion HPLC and sedimentation velocity experiments were performed with EmrE solubilized in N-dodecyl-beta-d-maltopyranoside (DM… (More)

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@article{Winstone2005OrganicSE, title={Organic solvent extracted EmrE solubilized in dodecyl maltoside is monomeric and binds drug ligand.}, author={Tara M. L. Winstone and Marie Jidenko and Marc le Maire and Christine Ebel and Karen A Duncalf and Raymond J Turner}, journal={Biochemical and biophysical research communications}, year={2005}, volume={327 2}, pages={437-45} }