Organic cation uptake is enhanced in bcrp1-transfected MDCKII cells.

Abstract

Stably transfected cell models are routinely used to examine drug-transporter interactions. In one such model of bcrp1-transfected MDCKII cells, we observed a significant enhancement of organic cation intracellular accumulation. Therefore, our goal was to further explore the expression and functional consequences of this cation transport system. Transport… (More)
DOI: 10.1021/mp900177r

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