Organic cation transporters.

  title={Organic cation transporters.},
  author={Giuliano Ciarimboli},
  journal={Xenobiotica; the fate of foreign compounds in biological systems},
  volume={38 7-8},
1. Organic cation transporters (OCTs) translocate endogenous (e.g. dopamine) and exogenous (e.g. drugs) substances of cationic nature and, therefore, play an important role in the detoxification of exogenous compounds. This review aims to furnish essential information on OCTs, with an emphasis on pharmacological aspects. 2. Analysis of the literature on OCTs makes clear that there is a species- and organ-specific distribution of the different isoforms, which can also be differentially regulated… CONTINUE READING
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