Organic cation transporter 3 (Slc22a3) is implicated in salt-intake regulation.

@article{Vialou2004OrganicCT,
  title={Organic cation transporter 3 (Slc22a3) is implicated in salt-intake regulation.},
  author={Vincent F. Vialou and Anne Amphoux and Ronald Zwart and Bruno Giros and Sophie Gautron},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2004},
  volume={24 11},
  pages={2846-51}
}
Organic cation transporters (OCTs) are carrier-type permeases known to participate in general detoxification functions in peripheral tissues. Previous in vitro studies have suggested that OCTs ensure Uptake2, a low-affinity, corticosteroid-sensitive catecholamine removal system, which was characterized initially in sympathetically innervated tissues. Although the presence of both Uptake(2)-like transport and most OCT subtypes has also been demonstrated in the brain, the physiological role of… CONTINUE READING

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