Organic anion-transporting ATPase of rat liver. II. Functional reconstitution of active transport and regulation by phosphorylation.

@article{Pikula1994OrganicAA,
  title={Organic anion-transporting ATPase of rat liver. II. Functional reconstitution of active transport and regulation by phosphorylation.},
  author={Slawomir Pikula and James B. Hayden and Sanjay Awasthi and Yogesh C. Awasthi and Piotr Zimniak},
  journal={The Journal of biological chemistry},
  year={1994},
  volume={269 44},
  pages={27574-9}
}
We have previously purified to homogeneity from rat liver plasma membranes a 90-kDa glycoprotein with S-(2,4-dinitrophenyl)glutathione-stimulated ATPase activity and other properties which identify it as the multispecific organic anion transporter (MOAT) specific for the transport into bile of non-bile acid organic anions (Pikula, S., Hayden, J. B., Awasthi, S., Awasthi, Y. C., and Zimniak, P. (1994) J. Biol. Chem. 269, 27566-27573). In the present communication, we report the functional… CONTINUE READING