Organic anion transporter (Slc22a) family members as mediators of toxicity.

  title={Organic anion transporter (Slc22a) family members as mediators of toxicity.},
  author={Douglas H. Sweet},
  journal={Toxicology and applied pharmacology},
  volume={204 3},
Exposure of the body to toxic organic anions is unavoidable and occurs from both intentional and unintentional sources. Many hormones, neurotransmitters, and waste products of cellular metabolism, or their metabolites, are organic anions. The same is true for a wide variety of medications, herbicides, pesticides, plant and animal toxins, and industrial chemicals and solvents. Rapid and efficient elimination of these substances is often the body's best defense for limiting both systemic exposure… CONTINUE READING
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