Organic anion secretion in polycystic kidney disease.

  title={Organic anion secretion in polycystic kidney disease.},
  author={George A. Tanner and Norbert Gretz and Youzhi Shao and Andrew P. Evan and M. Steinhausen},
  journal={Journal of the American Society of Nephrology : JASN},
  volume={8 8},
This study examined whether organic anion secretion contributes to fluid accumulation in cysts in polycystic kidney disease. Clearance and micropuncture studies were done on young (7 to 16 wk old), mostly male, heterozygous Han:SPRD cystic rats and healthy control littermate rats. Heterozygous Han:SPRD rats manifest a slowly progressive autosomal dominant… CONTINUE READING