Organic Anion Transporter 2: An Enigmatic Human Solute Carrier.

  title={Organic Anion Transporter 2: An Enigmatic Human Solute Carrier.},
  author={Hong Shen and Yurong Lai and A. David Rodrigues},
  journal={Drug metabolism and disposition: the biological fate of chemicals},
  volume={45 2},
As a member of the solute carrier 22A (SLC22A) family, organic anion transporter 2 (OAT2; SLC22A7) is emerging as an important drug transporter because of its expression in both the liver and kidney, two major eliminating organs, and its ability to transport not only a wide variety of xenobiotics but also numerous physiologically important endogenous compounds, like creatinine and cGMP. However, OAT2 has received relatively little attention compared with other OATs and solute carriers (SLCs… CONTINUE READING
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