Organelle proteomics: implications for subcellular fractionation in proteomics.

  title={Organelle proteomics: implications for subcellular fractionation in proteomics.},
  author={Lukas A. Huber and Kristian Pfaller and Ilja Vietor},
  journal={Circulation research},
  volume={92 9},
Functional proteome analysis is not restricted to the sequence information but includes the broad spectrum of structural modifications and quantitative changes of proteins to which they are subjected in different tissues and cell organelles and during the development of an organism. Cell biology has provided the means required for the analysis of the composition and properties of purified cellular elements. Subcellular fractionation is an approach universal across all cell types and tissues… CONTINUE READING
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