Organelle inheritance—what players have skin in the game?

@article{Gruneberg2017OrganelleIP,
  title={Organelle inheritance—what players have skin in the game?},
  author={Ulrike Gruneberg and Francis A. Barr},
  journal={Science},
  year={2017},
  volume={355},
  pages={459 - 460}
}
Peroxisomes contribute to cell division and differentiation decisions in the mammalian epidermis The concept of a checkpoint that monitors chromosome attachment to microtubules, and the discovery of the mitotic spindle assembly checkpoint proteins constituted a major milestone in understanding eukaryotic cell division (1). Chromosomes, however, are not the only constituents that have to be partitioned. Membrane-bound organelles such as the endoplasmic reticulum, Golgi apparatus, endosomes, and… 
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Where have all the cell organelles gone during the cell division?l.

References

SHOWING 1-10 OF 10 REFERENCES
Coupling organelle inheritance with mitosis to balance growth and differentiation
TLDR
The earliest molecular events associated with the commitment of epidermal progenitors to their differentiation program are defined and a genetic screen is conducted to identify which of the gene changes that occur in both early cell commitment and cancer are integral to maintaining the balance between growth and differentiation.
Regulation of mitotic spindle orientation: an integrated view
TLDR
The dynamic nature of the assembly of the Gαi/LGN/NuMA complex is highlighted and the molecular regulation of its localization is discussed and the influence of cell geometry and mechanical forces on spindle orientation is discussed.
Mitotic Golgi disassembly is required for bipolar spindle formation and mitotic progression
TLDR
It is demonstrated that Golgi disassembly is required for mitotic progression because failure to vesiculate the Golgi activates the canonical SAC, suggesting that cells actively monitor Golgi integrity in mitosis.
Aurora-A: the maker and breaker of spindle poles
TLDR
Recent advances in determining the early mitotic role of Aurora-A are discussed, with a strong emphasis on its function at the mitotic spindle poles.
PEX11β Deficiency Is Lethal and Impairs Neuronal Migration but Does Not Abrogate Peroxisome Function
TLDR
It is shown that mice lacking peroxisomal membrane protein PEX11β display several pathologic features shared by these mouse models of Zellweger syndrome, including neuronal migration defects, enhanced neuronal apoptosis, a developmental delay, hypotonia, and neonatal lethality.
Golgi Partitioning Controls Mitotic Entry through Aurora-A Kinase
TLDR
It is shown that a block of Golgi partitioning control G2/M progression through the impairment of centrosome recruitment and activation of Aurora-A in cell cycle arrest at the G2 stage.