Organelle autoregulation-stress responses in the ER, Golgi, mitochondria and lysosome.

  title={Organelle autoregulation-stress responses in the ER, Golgi, mitochondria and lysosome.},
  author={Kanae Sasaki and Hiderou Yoshida},
  journal={Journal of biochemistry},
  volume={157 4},
Organelle autoregulation is a homeostatic mechanism to regulate the capacity of each organelle according to cellular demands. The endoplasmic reticulum (ER) stress response increases the expression of ER chaperones and ER-associated degradation factors when the capacity of the ER becomes insufficient, e.g. during cellular differentiation or viral propagation, and which can be restored through increased synthesis of secretory or membrane proteins. In the Golgi stress response, insufficient… CONTINUE READING
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