Organellar dysfunction in the pathogenesis of pancreatitis.

  title={Organellar dysfunction in the pathogenesis of pancreatitis.},
  author={I. Ya. Gukovsky and Stephen J Pandol and Anna S. Gukovskaya},
  journal={Antioxidants & redox signaling},
  volume={15 10},
SIGNIFICANCE Acute pancreatitis is an inflammatory disease of exocrine pancreas that carries considerable morbidity and mortality; its pathophysiology remains poorly understood. During the past decade, new insights have been gained into signaling pathways and molecules that mediate the inflammatory response of pancreatitis and death of acinar cells (the… CONTINUE READING