Organ-specificity and diagnostic value of cell-mediated immunity against a liver-specific membrane protein: Studies in hepatic and non-hepatic diseases

@article{MeyerzumBschenfelde2005OrganspecificityAD,
  title={Organ-specificity and diagnostic value of cell-mediated immunity against a liver-specific membrane protein: Studies in hepatic and non-hepatic diseases},
  author={Karl‐Hermann Meyer zum B{\"u}schenfelde and Alfredo Alberti and Wilfred Niels Arnold and J. Freudenberg},
  journal={Klinische Wochenschrift},
  year={2005},
  volume={53},
  pages={1061-1067}
}
ZusammenfassungBei Patienten mit chronisch-aktiver Hepatitis (CAH) (n=58) konnte bei 70% der HBsAg-negativen und 48% der HBsAg-positiven Fälle eine zelluläre Immunreaktion (CMI) gegenüber humanen leberspezifischen Proteinen (HLPI) aus Plasmamembranen nachgewiesen werden.Mit HBsAg als Antigen war nur bei 12% der HBsAg-negativen und 24% der HBsAg-positiven CAH eine CMI vorhanden. Unter Berücksichtigung von HBsAg und Autoantikörpern im Serum von Patienten mit CAH konnte eine Einteilung in 4… Expand
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