Organ-specific markers in circulating tumor cell screening: an early indicator of metastasis-capable malignancy.

@article{PaterliniBrchot2011OrganspecificMI,
  title={Organ-specific markers in circulating tumor cell screening: an early indicator of metastasis-capable malignancy.},
  author={Patrizia Paterlini-Br{\'e}chot},
  journal={Future oncology},
  year={2011},
  volume={7 7},
  pages={849-71}
}
Circulating tumor cells (CTCs) represent an important biological link in the spread of primary solid tumors to the metastatic disease responsible for most cancer mortality. Their detection in the peripheral blood of patients with many different carcinomas has shown that tumor-cell dissemination can proceed at an early stage of tumor development and their presence is associated with poor clinical outcomes, particularly in metastatic disease. In this article we describe how the increasingly… CONTINUE READING

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