Organ-specific autoimmunity in patients with premature ovarian failure.


The diagnosis of premature ovarian failure (POF) was made in 45 women (aged 14 to 39 yr) with high concentrations of FSH and LH. Sera from these patients and a control group of 28 women were used to detect organ-specific autoantibodies. Eighteen patients with POF (40%) were positive for at least one autoantibody. In the control group only one woman (3.6… (More)


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@article{Belvisi1993OrganspecificAI, title={Organ-specific autoimmunity in patients with premature ovarian failure.}, author={Laura Belvisi and Ferdinando Bombelli and Luigi Sironi and Nicola Doldi}, journal={Journal of endocrinological investigation}, year={1993}, volume={16 11}, pages={889-92} }