Organ-on-a-chip platforms for studying drug delivery systems.

@article{Bhise2014OrganonachipPF,
  title={Organ-on-a-chip platforms for studying drug delivery systems.},
  author={Nupura S. Bhise and Jo{\~a}o Ribas and Vijayan Manoharan and Yu Shrike Zhang and Alessandro Polini and Solange Massa and Mehmet R. Dokmeci and Ali Khademhosseini},
  journal={Journal of controlled release : official journal of the Controlled Release Society},
  year={2014},
  volume={190},
  pages={
          82-93
        }
}
Novel microfluidic tools allow new ways to manufacture and test drug delivery systems. Organ-on-a-chip systems - microscale recapitulations of complex organ functions - promise to improve the drug development pipeline. This review highlights the importance of integrating microfluidic networks with 3D tissue engineered models to create organ-on-a-chip platforms, able to meet the demand of creating robust preclinical screening models. Specific examples are cited to demonstrate the use of these… CONTINUE READING

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