Organ metabolic rates and aging: two hypotheses.

  title={Organ metabolic rates and aging: two hypotheses.},
  author={James Adam Greenberg},
  journal={Medical hypotheses},
  volume={52 1},
There is currently no satisfactory explanation for caloric restriction's (CR's) well-established ability to reduce the rate of aging. Pearl's rate of living theory postulates a direct relationship between metabolic rates and the rate of aging, but CR, exercise and cold-exposure studies have shown that this theory is not valid in rodents with respect to whole-body energy metabolism. The present paper describes a crude analysis of previously published data from rat CR, wheel running and cold… CONTINUE READING

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