Organ dysfunction after cardiopulmonary bypass. A systemic inflammatory reaction initiated by the extracorporeal circuit

@article{Westaby1987OrganDA,
  title={Organ dysfunction after cardiopulmonary bypass. A systemic inflammatory reaction initiated by the extracorporeal circuit},
  author={Steve Westaby},
  journal={Intensive Care Medicine},
  year={1987},
  volume={13},
  pages={89-95}
}
Since the first open heart operations in the 1950s cardiopulmonary bypass (CPB) has been known to contribute to the mortality and morbidity of cardiac surgery [1 3]. In 1985 when hospital mortality for some groups of patients is less than 1%, modern CPB seems well tolerated, yet as the scope of cardiac surgery extends to younger infants and older adults with more complex lesions, the probability of experiencing clinical manifestations of perfusion damage increases [4, 5]. Collectively these… CONTINUE READING

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