Organ distribution and molecular forms of human xanthine dehydrogenase/xanthine oxidase protein.

@article{Sarnesto1996OrganDA,
  title={Organ distribution and molecular forms of human xanthine dehydrogenase/xanthine oxidase protein.},
  author={Annikki Sarnesto and Nina Linder and Kari O. Raivio},
  journal={Laboratory investigation; a journal of technical methods and pathology},
  year={1996},
  volume={74 1},
  pages={48-56}
}
Xanthine dehydrogenase/xanthine oxidase (XDH/XO) is a major cytoplasmic source of superoxide radicals and hydrogen peroxide, and it is considered important in the pathogenesis of ischemia-reperfusion damage. Because little is known about the enzyme in human tissues, the aims of this study were to purify human XDH/XO and to produce Ab for detection of the… CONTINUE READING