Organ Culture as a Model System for Studies on Enterotoxin Interactions with the Intestinal Epithelium.

@article{Lorenzen2016OrganCA,
  title={Organ Culture as a Model System for Studies on Enterotoxin Interactions with the Intestinal Epithelium.},
  author={Ulver Spangsberg Lorenzen and Gert Helge Hansen and E Michael Danielsen},
  journal={Methods in molecular biology},
  year={2016},
  volume={1396},
  pages={159-166}
}
Studies on bacterial enterotoxin-epithelium interactions require model systems capable of mimicking the events occurring at the molecular and cellular levels during intoxication. In this chapter, we describe organ culture as an often neglected alternative to whole-animal experiments or enterocyte-like cell lines. Like cell culture, organ culture is versatile and suitable for studying rapidly occurring events, such as enterotoxin binding and uptake. In addition, it is advantageous in offering an… CONTINUE READING

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