Orexin modulates brown adipose tissue thermogenesis.

  title={Orexin modulates brown adipose tissue thermogenesis.},
  author={Christopher J. Madden and Domenico Tupone and Shaun F. Morrison},
  journal={Biomolecular concepts},
  volume={3 4},
Non-shivering thermogenesis in brown adipose tissue (BAT) plays an important role in thermoregulation. In addition, activations of BAT have important implications for energy homeostasis due to the metabolic consumption of energy reserves entailed in the production of heat in this tissue. In this conceptual overview we describe the role of orexins/hypocretins within the central nervous system in the modulation of thermogenesis in BAT under several physiological conditions. Within this framework… CONTINUE READING

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