Orexin Projections and Localization of Orexin Receptors

  title={Orexin Projections and Localization of Orexin Receptors},
  author={Jacob N. Marcus and Joel K Elmquist}
The past several years have provided important insights into the physiological significance of the central orexin system. An important component of these is an increased understanding of the unique neuroanatomy of the orexin/hypocretin system. The orexin peptides, orexin-A and orexin-B, are produced in a restricted region of the central nervous system, the neurons of the lateral hypothalamic area. From this small neuronal source, on the order of a few thousand neurons, orexin-expressing neurons… CONTINUE READING