Orexin A mediation of time spent moving in rats: neural mechanisms.

  title={Orexin A mediation of time spent moving in rats: neural mechanisms.},
  author={Catherine M. Kotz and Chaoping Wang and Jennifer A Teske and Andrew J. Thorpe and Colleen M. Novak and Kohji Kiwaki and James A. Levine},
  volume={142 1},
The brain regulates energy balance and spontaneous physical activity, including both small- and large-motor activities. Neural mediators of spontaneous physical activity are currently undefined, although the amount of time spent in sedentary positions versus standing and ambulating may be important in the energetics of human obesity. Orexin A, a neuropeptide produced in caudal hypothalamic areas and projecting throughout the neuraxis, enhances arousal and spontaneous physical activity. To test… CONTINUE READING
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