Orexigenic peptides and alcohol intake: differential effects of orexin, galanin, and ghrelin.

@article{Schneider2007OrexigenicPA,
  title={Orexigenic peptides and alcohol intake: differential effects of orexin, galanin, and ghrelin.},
  author={Eve Rebecca Schneider and Pedro V Rada and Ryan D Darby and Sarah F. Leibowitz and Bartley G. Hoebel},
  journal={Alcoholism, clinical and experimental research},
  year={2007},
  volume={31 11},
  pages={1858-65}
}
BACKGROUND The question is which hypothalamic systems for food intake might play a role in ethanol intake and contribute to alcohol abuse. The peptide orexin was found to exhibit similar properties to galanin in its relation to dietary fat and may therefore be similar to galanin in having a stimulatory effect on alcohol intake. METHODS Rats were trained to drink 10% ethanol, implanted with brain cannulas, and then injected in the paraventricular nucleus (PVN), lateral hypothalamus (LH), or… CONTINUE READING