Ordered-subset analysis of savant skills in autism for 15q11-q13.

  title={Ordered-subset analysis of savant skills in autism for 15q11-q13.},
  author={Deqiong Ma and James M. Jaworski and Marisa M Menold and Sin{\'e}ad Donnelly and Ruth K. Abramson and Harry H. Wright and G. Robert Delong and John R. Gilbert and Margaret A. Pericak-Vance and Michael L. Cuccaro},
  journal={American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics},
  volume={135B 1},
Autism is a complex disorder characterized by genetic and phenotypic heterogeneity. Analysis of phenotypically homogeneous subtypes has been used to both confirm and narrow potential autism linkage regions such as the chromosomal region 15q11-q13. Increased evidence for linkage in this region had been found in a subgroup of 21 autism families (total families = 94) stratified based on a savant skill factor (SSF) from the Autism Diagnostic Interview, Revised (ADI-R). We examined the savant… CONTINUE READING