Ordered self-assembled locked nucleic acid (LNA) structures on gold(111) surface with enhanced single base mismatch recognition capability.

@article{Mishra2012OrderedSL,
  title={Ordered self-assembled locked nucleic acid (LNA) structures on gold(111) surface with enhanced single base mismatch recognition capability.},
  author={Sourav Mishra and Srabani Ghosh and Rupa Mukhopadhyay},
  journal={Langmuir : the ACS journal of surfaces and colloids},
  year={2012},
  volume={28 9},
  pages={
          4325-33
        }
}
Locked nucleic acid (LNA) is a conformationally restricted nucleic acid analogue, which is potentially a better alternative than DNA for application in the nucleic acid based biosensor technologies, due to its efficient and sequence-specific DNA/RNA detection capability and lack of molecule-surface interaction on solid surfaces, compared to DNA. We report, for the first time, a straightforward way (based on simple immersion method) of generating an ordered self-assembled LNA monolayer, which is… CONTINUE READING
BETA

References

Publications referenced by this paper.
SHOWING 1-10 OF 59 REFERENCES

Molecular Structure of Monolayers from Thiol-Terminated Polyimide Model Compounds on Gold. 1. A Spectroscopic Investigation

  • J. T. Young, F. J. Boerio, Z. Zhang, T. L. Beck
  • surface. J. Colloid Interface Sci
  • 2011

self-assembled monolayers based biomolecular electronic device. Biosens. Bioelectron

  • J. Sharma, R. Chhabra, C. S. Andersen, K. V. Gothelf, H. Yan, Y. Liu
  • J. Am. Chem. Soc
  • 2009

Similar Papers

Loading similar papers…