Order parameters of unsaturated phospholipids in membranes and the effect of cholesterol: a 1H–13C solid-state NMR study at natural abundance

@article{Warschawski2005OrderPO,
  title={Order parameters of unsaturated phospholipids in membranes and the effect of cholesterol: a 1H–13C solid-state NMR study at natural abundance},
  author={Dror E. Warschawski and Philippe F. Devaux},
  journal={European Biophysics Journal},
  year={2005},
  volume={34},
  pages={987-996}
}
Most biological phospholipids contain at least one unsaturated alkyl chain. However, few order parameters of unsaturated lipids have been determined because of the difficulty associated with isotopic labeling of a double bond. Dipolar recoupling on axis with scaling and shape preservation (DROSS) is a solid-state nuclear magnetic resonance technique optimized for measuring 1H–13C dipolar couplings and order parameters in lipid membranes in the fluid phase. It has been used to determine the… CONTINUE READING