Orchiectomy Markedly Reduces the Concentration of the Three Isoforms of Transforming Growth Factor β in Rat Bone, and Reduction Is Prevented by Testosterone.


Available evidence indicates that transforming growth factor b (TGFb) is produced by bone cells, that production is enhanced by testosterone and dihydrotestosterone, and that TGFb is an important modulator of bone formation, induction, and repair. To determine the relative concentrations of isoforms of skeletal TGFb, whether orchiectomy alters the… (More)
DOI: 10.1210/endo.139.2.5717


6 Figures and Tables

Slides referencing similar topics