Orchestrating the network of molecular pathways affecting aging: Role of nonselective autophagy and mitophagy.


Autophagy is best known as a mechanism involved in cellular recycling of biomolecules during periods of nutritional starvation. More recently, an additional function of autophagy emerged: the selective degradation of functionally impaired or surplus proteins, organelles and invading bacteria. With this function autophagy is integrated in a network of… (More)
DOI: 10.1016/j.mad.2016.01.003

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