Orbital and intraocular myofibroblastoma.


A 66-year-old woman presented with a blind, painful, hypertensive, and proptotic left eye. Computed tomographic imaging revealed a well-circumscribed mass involving the left orbit and globe. Metastatic work-up failed to reveal extraorbital lesions and the tumor was removed in toto via an evisceration approach orbitotomy. Histopathology and immunohistochemistry were most consistent with mammary-type myofibroblastoma with fascicles of bland, uniform spindle cells that stained positive for desmin and CD34. We are not aware of previous reports of orbital or ocular myofibroblastoma. This neoplasm has not been shown to recur, undergo malignant transformation, or metastasize. Familiarity with its clinical, histopathologic, and immunohistochemical features may improve diagnostic accuracy and treatment decisions for patients presenting with similar findings.

DOI: 10.3109/01676830.2013.871301
Citations per Year

1,100 Citations

Semantic Scholar estimates that this publication has 1,100 citations based on the available data.

See our FAQ for additional information.

Cite this paper

@article{Costin2014OrbitalAI, title={Orbital and intraocular myofibroblastoma.}, author={Bryan R Costin and Thomas P. Plesec and Tal J. Rubinstein and Carlos A. Medina and Arun Singh and John R. Goldblum and Julian D Perry}, journal={Orbit}, year={2014}, volume={33 3}, pages={202-5} }