Orally administered glucans from the edible mushroom Pleurotus pulmonarius reduce acute inflammation in dextran sulfate sodium-induced experimental colitis.

@article{Lavi2010OrallyAG,
  title={Orally administered glucans from the edible mushroom Pleurotus pulmonarius reduce acute inflammation in dextran sulfate sodium-induced experimental colitis.},
  author={Iris Lavi and Dana Levinson and Irena Peri and Lili Nimri and Yitzhak Hadar and Betty Schwartz},
  journal={The British journal of nutrition},
  year={2010},
  volume={103 3},
  pages={
          393-402
        }
}
Polysaccharides are one of the most potent mushroom-derived substances exhibiting anti-inflammatory and immunomodulatory properties. The aims of the present study were to determine whether orally administered glucans from the edible mushroom Pleurotus pulmonarius could attenuate or prevent the development of experimental colitis in mice. Colonic inflammation was induced in mice by treatment with 3.5 % dextran sulfate sodium (DSS) for 18 d. Before or after DSS administration, mice were given hot… CONTINUE READING

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